Paul Mitaari Magwene

Associate Professor of Biology

Office: 
124 Science Drive, Room 4103 Ffsc, Duke Box 90338, Durham, NC 27708
Campus Box: 
Box 90338, Durham, NC 27708
Phone: 
(919) 613-8159

Education

  • Ph.D., University of Chicago 1999

Ehrenreich, IM, and Magwene, PM. "Genetic Analysis of Complex Traits in Saccharomyces cerevisiae." Cold Spring Harbor protocols 2017, no. 6 (June 2017): pdb.top077602-. Full Text

Ehrenreich, IM, and Magwene, PM. "Genetic Dissection of Heritable Traits in Yeast Using Bulk Segregant Analysis." Cold Spring Harbor protocols 2017, no. 6 (June 2017): pdb.prot088989-. Full Text

Skelly, DA, Magwene, PM, Meeks, B, and Murphy, HA. "Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains." Proceedings. Biological sciences 284, no. 1852 (April 2017). Full Text

Maxwell, CS, and Magwene, PM. "When sensing is gambling: An experimental system reveals how plasticity can generate tunable bet-hedging strategies." Evolution; international journal of organic evolution 71, no. 4 (April 2017): 859-871. Full Text

Maxwell, CS, and Magwene, PM. "The quick and the dead: microbial demography at the yeast thermal limit." Molecular ecology 26, no. 6 (March 2017): 1631-1640. Full Text

Skelly, DA, and Magwene, PM. "Population perspectives on functional genomic variation in yeast." Briefings in functional genomics 15, no. 2 (March 2016): 138-146. (Review) Full Text

Skelly, DA, Magwene, PM, and Stone, EA. "Sporadic, Global Linkage Disequilibrium Between Unlinked Segregating Sites." Genetics 202, no. 2 (February 2016): 427-437. Full Text

Strope, PK, Kozmin, SG, Skelly, DA, Magwene, PM, Dietrich, FS, and McCusker, JH. "2μ plasmid in Saccharomyces species and in Saccharomyces cerevisiae." FEMS yeast research 15, no. 8 (December 2015). Full Text

Strope, PK, Skelly, DA, Kozmin, SG, Mahadevan, G, Stone, EA, Magwene, PM, Dietrich, FS, and McCusker, JH. "The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen." Genome research 25, no. 5 (May 2015): 762-774. Full Text

Magwene, PM. "Revisiting mortimer's genome renewal hypothesis: Heterozygosity, homothallism, and the potential for adaptation in yeast." Advances in Experimental Medicine and Biology 781 (January 1, 2014): 37-48. Full Text

Pages

The Genetic Basis of Virulence in Cryptococcus Neoformans awarded by National Institutes of Health (Principal Investigator). 2017 to 2022

Nuclear, mitochondrial and L-A virus contributions to yeast quantitative traits awarded by National Institutes of Health (Co Investigator). 2017 to 2021

Organization and Function of Cellular Structure awarded by National Institutes of Health (Mentor). 1975 to 2020

Molecular Mycology and Pathogenesis Training Program awarded by National Institutes of Health (Mentor). 2015 to 2019

The Genetic Architecture of Virulence in Cryptococcus neoformans awarded by National Institutes of Health (Principal Investigator). 2017

High throughput S. cerevisiae HAM, GWA & QT/QTL architecture awarded by National Institutes of Health (Co-Principal Investigator). 2011 to 2016

Functional Variation in a Conserved Pathway Influencing Cellular Differentiation awarded by National Institutes of Health (Principal Investigator). 2014 to 2016

Causes and Consequences of Variation in cyclic AMP - Protein Kinase A Signaling in Yeast awarded by National Science Foundation (Principal Investigator). 2013 to 2016

Collaborative Reseach: The Genomics of Adaptation in Experimental Yeast Populations During Short and Long-Term Selection awarded by National Science Foundation (Principal Investigator). 2010 to 2015

Research Initiation Grant: The Effects of Genetic Variation on Gene Networks in Yeast awarded by National Science Foundation (Principal Investigator). 2006 to 2009