Gregory Allan Wray
Ph.D., Duke University 1987
B.S., College of William and Mary 1981
Benito-Kwiecinski, Silvia, Stefano L. Giandomenico, Magdalena Sutcliffe, Erlend S. Riis, Paula Freire-Pritchett, Iva Kelava, Stephanie Wunderlich, et al. “An early cell shape transition drives evolutionary expansion of the human forebrain.” Cell, March 19, 2021. https://doi.org/10.1016/j.cell.2021.02.050. Full Text
Markunas, Alexandra M., Perathu K. R. Manivannan, Jordan E. Ezekian, Agnim Agarwal, William Eisner, Katherina Alsina, Hugh D. Allen, et al. “TBX5-encoded T-box transcription factor 5 variant T223M is associated with long QT syndrome and pediatric sudden cardiac death.” Am J Med Genet A 185, no. 3 (March 2021): 923–29. https://doi.org/10.1002/ajmg.a.62037. Full Text Open Access Copy
Song, Hao, Ximing Guo, Lina Sun, Qianghui Wang, Fengming Han, Haiyan Wang, Gregory A. Wray, et al. “The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia.” Bmc Biology 19, no. 1 (January 25, 2021): 15. https://doi.org/10.1186/s12915-020-00943-9. Full Text
Byrne, M., D. Koop, D. Strbenac, P. Cisternas, J. Y. H. Yang, P. L. Davidson, and G. Wray. “Transcriptomic analysis of Nodal – and BMP- associated genes during development to the juvenile seastar in Parvulastra exigua (Asterinidae).” Marine Genomics, January 1, 2021. https://doi.org/10.1016/j.margen.2021.100857. Full Text
Massri, Abdull J., Geoffrey R. Schiebinger, Alejandro Berrio, Lingyu Wang, Gregory A. Wray, and David R. McClay. “Methodologies for Following EMT In Vivo at Single Cell Resolution.” Methods in Molecular Biology (Clifton, N.J.) 2179 (January 2021): 303–14. https://doi.org/10.1007/978-1-0716-0779-4_23. Full Text
Devens, Hannah R., Phillip L. Davidson, Dione J. Deaker, Kathryn E. Smith, Gregory A. Wray, and Maria Byrne. “Ocean acidification induces distinct transcriptomic responses across life history stages of the sea urchin Heliocidaris erythrogramma.” Molecular Ecology 29, no. 23 (December 2020): 4618–36. https://doi.org/10.1111/mec.15664. Full Text
Berrio, Alejandro, Valerie Gartner, and Gregory Wray. “Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function,” September 16, 2020. https://doi.org/10.1101/2020.09.16.300038. Full Text Open Access Copy
Davidson, Phillip L., Haobing Guo, Lingyu Wang, Alejandro Berrio, He Zhang, Yue Chang, Andrew L. Soborowski, David R. McClay, Guangyi Fan, and Gregory A. Wray. “Chromosomal-Level Genome Assembly of the Sea Urchin Lytechinus variegatus Substantially Improves Functional Genomic Analyses.” Genome Biology and Evolution 12, no. 7 (July 2020): 1080–86. https://doi.org/10.1093/gbe/evaa101. Full Text
Wang, Lingyu, Jennifer W. Israel, Allison Edgar, Rudolf A. Raff, Elizabeth C. Raff, Maria Byrne, and Gregory A. Wray. “Genetic basis for divergence in developmental gene expression in two closely related sea urchins.” Nature Ecology & Evolution 4, no. 6 (June 2020): 831–40. https://doi.org/10.1038/s41559-020-1165-y. Full Text
Berrio, Alejandro, Ralph Haygood, and Gregory A. Wray. “Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral.” Bmc Genomics 21, no. 1 (May 13, 2020): 359. https://doi.org/10.1186/s12864-020-6752-4. Full Text Open Access Copy
Babbitt, C. C., L. W. Pfefferle, G. E. Crawford, and G. A. Wray. “Evolution of gene expression network underlying a disease state.” In Integrative and Comparative Biology, 55:E7–E7. OXFORD UNIV PRESS INC, 2015.
Bauernfeind, Amy L., Michelle L. Reyzer, Richard M. Caprioli, John J. Ely, Courtney C. Babbitt, Gregory A. Wray, Patrick R. Hof, and Chet C. Sherwood. “Differences in energy metabolism in the brains of humans and chimpanzees: a study of protein expression.” In American Journal of Physical Anthropology, 156:80–80. WILEY-BLACKWELL, 2015.
Babbitt, Courtney C., and Gregory A. Wray. “Evolution of gene expression network underlying a disease state in humans and non-human primates.” In American Journal of Physical Anthropology, 156:74–74. WILEY-BLACKWELL, 2015.
Bauernfeind, Amy L., Erik J. Soderblom, Meredith E. Turner, Arthur M. Moseley, John J. Ely, Patrick R. Hof, Chet C. Sherwood, Gregory A. Wray, and Courtney C. Babbitt. “Differential gene and protein expression in the human and chimpanzee brain: A comparison using high-throughput techniques.” In American Journal of Physical Anthropology, 153:73–73. WILEY-BLACKWELL, 2014.
Wygoda, J. A., M. Byrne, D. R. Mcclay, and G. A. Wray. “Shifts in the Expression of Developmental Regulatory Genes Involved in the Evolution of a Novel Life History Difference.” In Integrative and Comparative Biology, 54:E230–E230. OXFORD UNIV PRESS INC, 2014.
Wygoda, J. A., D. Koop, J. Yang, G. A. Wray, and M. Byrne. “Developmental Transcriptome of Heliociaris erythrogramma - from bilateral larva to radial juvenile.” In Integrative and Comparative Biology, 54:E372–E372. OXFORD UNIV PRESS INC, 2014.
Wray, G. A., D. Garfield, and D. Runcie. “Evolution of an embryonic gene regulatory network in the sea urchin Strongylocentrotus purpuratus.” In Echinoderms in a Changing World, edited by C. Johnson, 276–276. CRC PRESS-TAYLOR & FRANCIS GROUP, 2013.
Runcie, D. E., D. A. Garfield, C. C. Babbitt, A. Pfefferle, W. J. Nielsen, and G. A. Wray. “Phenotypic plasticity and the developmental regulatory network in the purple sea urchin.” In Echinoderms in a Changing World, edited by C. Johnson, 300–301. CRC PRESS-TAYLOR & FRANCIS GROUP, 2013.
Babbitt, C. C., L. W. Pfefferle, O. Fedrigo, and G. A. Wray. “Conservation and function of noncoding RNAs in primate evolution.” In Integrative and Comparative Biology, 52:E8–E8. OXFORD UNIV PRESS INC, 2012.
Horvath, Julie E., Christine Wu, Maxx Toler, Olivier Fedrigo, Lisa W. Pfefferle, Anthony Moore, Gowri L. Ramachandran, et al. “Enamel thickness in Microcebus murinus and Macaca mulana and the evolutionary genetics of enamel matrix proteins in hominoids.” In American Journal of Physical Anthropology, 147:168–168. WILEY-BLACKWELL, 2012.
AAAS Fellow. American Association for the Advancement of Science. February 16, 2019
Distinguished Visiting Professor. University of Miami. March 26, 2018
Genetic and Genomics Training Grant awarded by National Institutes of Health (Mentor). 2020 to 2025
The Duke FUNCTION Center: Pioneering the comprehensive identification of combinatorial noncoding causes of disease awarded by National Institutes of Health (Co-Principal Investigator). 2020 to 2023
Embryonic Cell Recognition: Specificity Determinants awarded by National Institutes of Health (Co-Principal Investigator). 1980 to 2023
Evolution of a developmental gene regulatory network during a life history switch in Heliocidaris awarded by National Science Foundation (Principal Investigator). 2019 to 2022
Preparing Genetic Counselors for Genomic Medicine Research awarded by National Institutes of Health (Co-Principal Investigator). 2017 to 2022
IRES Track 1 IRTG Engaged in Dissecting and Reengineering the Regulatory Genome awarded by National Science Foundation (Principal Investigator). 2019 to 2022
Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health (Mentor). 2001 to 2022
NRT: Integrative Bioinformatics for Investigating and Engineering Microbiomes (IBIEM) awarded by National Science Foundation (Co-Principal Investigator). 2015 to 2021
Natural Selection in Admixed Populations awarded by National Institutes of Health (Co-Sponsor). 2020 to 2021
Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health (Mentor). 2005 to 2021