Zhen-Ming Pei

Associate Professor of Biology

3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.


  • Ph.D., Shanghai Institute of Plant Physiology (China) 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Shang, Y., P. Yang, and Z. Pei. “Research at channel level on the effect of LaCl3 on Radish (Raphanus satirus L.) vacuolar membrane.” Chinese Science Bulletin 47, no. 2 (January 1, 2002): 112–15.

Yang, P., Y. F. Shang, and Z. M. Pei. “Action Mechanism Research of Lanthanons to Slow Vacuolar Ion Channels in Raphanus Satirus L. (Xinlimei) Radish by Patch-Clamp.” Chinese Chemical Letters 12, no. 9 (September 1, 2001): 813–14.

Pei, Z. M., Y. Murata, G. Benning, S. Thomine, B. Klüsener, G. J. Allen, E. Grill, and J. I. Schroeder. “Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells.Nature 406, no. 6797 (August 2000): 731–34. https://doi.org/10.1038/35021067. Full Text

Pei, Z. M., M. Ghassemian, C. M. Kwak, P. McCourt, and J. I. Schroeder. “Role of farnesyltransferase in ABA regulation of guard cell anion channels and plant water loss.Science (New York, N.Y.) 282, no. 5387 (October 1998): 287–90. https://doi.org/10.1126/science.282.5387.287. Full Text

Pei, Z. M., V. M. Baizabal-Aguirre, G. J. Allen, and J. I. Schroeder. “A transient outward-rectifying K+ channel current down-regulated by cytosolic Ca2+ in Arabidopsis thaliana guard cells.” Proceedings of the National Academy of Sciences of the United States of America 95, no. 11 (May 26, 1998): 6548–53. https://doi.org/10.1073/pnas.95.11.6548. Full Text

Pei, Z. M., J. I. Schroeder, and M. Schwarz. “Background ion channel activities in Arabidopsis guard cells and review of ion channel regulation by protein phosphorylation events.” Journal of Experimental Botany 49, no. SPEC. ISS. (January 1, 1998): 319–28. https://doi.org/10.1093/jxb/49.special_issue.319. Full Text

Ichida, A. M., Z. M. Pei, V. M. Baizabal-Aguirre, K. J. Turner, and J. I. Schroeder. “Expression of a Cs(+)-resistant guard cell K+ channel confers Cs(+)-resistant, light-induced stomatal opening in transgenic arabidopsis.The Plant Cell 9, no. 10 (October 1997): 1843–57. https://doi.org/10.1105/tpc.9.10.1843. Full Text