Zhen-Ming Pei

Associate Professor of Biology

3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.


  • Ph.D., Shanghai Institute of Plant Physiology (China) 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Liu, T. W., W. J. Hu, X. Q. Wang, L. Niu, B. Fu, F. H. Wu, Z. M. Pei, and H. L. Zheng. “RETRACTED ARTICLE: A 2-D DIGE analysis of simulated acid rain-responsive proteins in Pinus massoniana needles.” Trees  Structure and Function 26, no. 5 (October 1, 2012). https://doi.org/10.1007/s00468-012-0750-3. Full Text

Wang, Wen-Hua, Xiao-Qian Yi, Ai-Dong Han, Ting-Wu Liu, Juan Chen, Fei-Hua Wu, Xue-Jun Dong, Jun-Xian He, Zhen-Ming Pei, and Hai-Lei Zheng. “Calcium-sensing receptor regulates stomatal closure through hydrogen peroxide and nitric oxide in response to extracellular calcium in Arabidopsis.Journal of Experimental Botany 63, no. 1 (January 2012): 177–90. https://doi.org/10.1093/jxb/err259. Full Text

Huang, Shan-Shan, Juan Chen, Xue-Jun Dong, Janet Patton, Zhen-Ming Pei, and Hai-Lei Zheng. “Calcium and calcium receptor CAS promote Arabidopsis thaliana de-etiolation.Physiologia Plantarum 144, no. 1 (January 2012): 73–82. https://doi.org/10.1111/j.1399-3054.2011.01523.x. Full Text

Chen, Juan, Fei-Hua Wu, Ting-Wu Liu, Lei Chen, Qiang Xiao, Xue-Jun Dong, Jun-Xian He, Zhen-Ming Pei, and Hai-Lei Zheng. “Emissions of nitric oxide from 79 plant species in response to simulated nitrogen deposition.Environmental Pollution (Barking, Essex : 1987) 160, no. 1 (January 2012): 192–200. https://doi.org/10.1016/j.envpol.2011.09.007. Full Text

Tang, Xiang, Juan Chen, Wen-Hua Wang, Ting-Wu Liu, Jun Zhang, Ya-Hui Gao, Zhen-Ming Pei, and Hai-Lei Zheng. “The changes of nitric oxide production during the growth of Microcystis aerugrinosa.Environmental Pollution (Barking, Essex : 1987) 159, no. 12 (December 2011): 3784–92. https://doi.org/10.1016/j.envpol.2011.06.042. Full Text

Chen, Juan, Fei-Hua Wu, Wen-Hua Wang, Chen-Juan Zheng, Guang-Hui Lin, Xue-Jun Dong, Jun-Xian He, Zhen-Ming Pei, and Hai-Lei Zheng. “Hydrogen sulphide enhances photosynthesis through promoting chloroplast biogenesis, photosynthetic enzyme expression, and thiol redox modification in Spinacia oleracea seedlings.Journal of Experimental Botany 62, no. 13 (August 2011): 4481–93. https://doi.org/10.1093/jxb/err145. Full Text

Liu, Ting-Wu, Bin Fu, Li Niu, Juan Chen, Wen-Hua Wang, Jun-Xian He, Zhen-Ming Pei, and Hai-Lei Zheng. “Comparative proteomic analysis of proteins in response to simulated acid rain in Arabidopsis.Journal of Proteome Research 10, no. 5 (May 2011): 2579–89. https://doi.org/10.1021/pr200056a. Full Text

Liu, Tingwu, Xinwu Jiang, Wuliang Shi, Juan Chen, Zhenming Pei, and Hailei Zheng. “Comparative proteomic analysis of differentially expressed proteins in β-aminobutyric acid enhanced Arabidopsis thaliana tolerance to simulated acid rain.Proteomics 11, no. 10 (May 2011): 2079–94. https://doi.org/10.1002/pmic.201000307. Full Text

Liu, Ting-Wu, Fei-Hua Wu, Wen-Hua Wang, Juan Chen, Zhen-Ji Li, Xue-Jun Dong, Janet Patton, Zhen-Ming Pei, and Hai-Lei Zheng. “Effects of calcium on seed germination, seedling growth and photosynthesis of six forest tree species under simulated acid rain.Tree Physiology 31, no. 4 (April 6, 2011): 402–13. https://doi.org/10.1093/treephys/tpr019. Full Text

Zhu, Z., Z. M. Pei, and H. L. Zheng. “Effect of salinity on osmotic adjustment characteristics of Kandelia candel.” Russian Journal of Plant Physiology 58, no. 2 (March 1, 2011): 226–32. https://doi.org/10.1134/S1021443711020270. Full Text