Zhen-Ming Pei

Associate Professor of Biology

Office: 
3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
Phone: 
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.

Education

  • Ph.D., Shanghai Institute of Plant Physiology 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Pei, ZM, Murata, Y, Benning, G, Thomine, S, Klüsener, B, Allen, GJ, Grill, E, and Schroeder, JI. "Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells." Nature 406, no. 6797 (August 2000): 731-734. Full Text

Pei, ZM, Ghassemian, M, Kwak, CM, McCourt, P, and Schroeder, JI. "Role of farnesyltransferase in ABA regulation of guard cell anion channels and plant water loss." Science (New York, N.Y.) 282, no. 5387 (October 1998): 287-290. Full Text

Pei, Z-M, Baizabal-Aguirre, VM, Allen, GJ, and Schroeder, JI. "A transient outward-rectifying K+ channel current down-regulated by cytosolic Ca2+ in Arabidopsis thaliana guard cells." Proceedings of the National Academy of Sciences of the United States of America 95, no. 11 (1998): 6548-6553. Full Text

Pei, Z-M, Schroeder, JI, and Schwarz, M. "Background ion channel activities in Arabidopsis guard cells and review of ion channel regulation by protein phosphorylation events." Journal of Experimental Botany 49, no. SPEC. ISS. (1998): 319-328.

Ichida, AM, Pei, ZM, Baizabal-Aguirre, VM, Turner, KJ, and Schroeder, JI. "Expression of a Cs(+)-resistant guard cell K+ channel confers Cs(+)-resistant, light-induced stomatal opening in transgenic arabidopsis." The Plant Cell 9, no. 10 (October 1997): 1843-1857. Full Text

Pei, ZM, Kuchitsu, K, Ward, JM, Schwarz, M, and Schroeder, JI. "Differential abscisic acid regulation of guard cell slow anion channels in Arabidopsis wild-type and abi1 and abi2 mutants." The Plant Cell 9, no. 3 (March 1997): 409-423. Full Text

Pei, ZM, Ward, JM, Harper, JF, and Schroeder, JI. "A novel chloride channel in Vicia faba guard cell vacuoles activated by the serine/threonine kinase, CDPK." The Embo Journal 15, no. 23 (December 1996): 6564-6574. Full Text

Pei, Z, Fu, W, Guo, L, and Tang, Z. "Effect of salt stress on photosystem II heterogeneity in wheat leaves." Science in China, Series C: Life Sciences 39, no. 5 (1996): 501-510.

Ward, JM, Pei, Z-M, and Schroeder, JI. "Roles of ion channels in initiation of signal transduction in higher plants." Plant Cell 7 (1995): 833-844. (Academic Article)

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