Zhen-Ming Pei

Associate Professor of Biology

Office: 
3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
Phone: 
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.

Education

  • Ph.D., Shanghai Institute of Plant Physiology 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Yuan, F., H. Yang, Y. Xue, D. Kong, R. Ye, C. Li, J. Zhang, et al. “Corrigendum: OSCA1 mediates osmotic-stress-evoked Ca(2+) increases vital for osmosensing in Arabidopsis..” Nature, February 2015.

Yuan, Fang, Huimin Yang, Yan Xue, Dongdong Kong, Rui Ye, Chijun Li, Jingyuan Zhang, et al. “OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing in Arabidopsis..” Nature 514, no. 7522 (October 2014): 367–71. https://doi.org/10.1038/nature13593. Full Text

Wu, Xiaomei, Fei-Hua Wu, Xiaoqiang Wang, Lilin Wang, James N. Siedow, Weiguo Zhang, and Zhen-Ming Pei. “Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING..” Nucleic Acids Research 42, no. 13 (July 2014): 8243–57. https://doi.org/10.1093/nar/gku569. Full Text

Hu, W. -. J., J. Chen, T. -. W. Liu, Q. Wu, W. -. H. Wang, X. Liu, Z. -. J. Shen, et al. “Proteome and calcium-related gene expression in Pinus massoniana needles in response to acid rain under different calcium levels.” Plant and Soil, 2014.

Hu, W. J., J. Chen, T. W. Liu, Q. Wu, W. H. Wang, X. Liu, Z. J. Shen, et al. “Proteome and calcium-related gene expression in Pinus massoniana needles in response to acid rain under different calcium levels.” Plant and Soil 380, no. 1 (January 1, 2014): 285–303. https://doi.org/10.1007/s11104-014-2086-9. Full Text

Liu, Wei-Zhong, Dong-Dong Kong, Xue-Xin Gu, Hong-Bo Gao, Jin-Zheng Wang, Min Xia, Qian Gao, et al. “Cytokinins can act as suppressors of nitric oxide in Arabidopsis..” Proceedings of the National Academy of Sciences of the United States of America 110, no. 4 (January 14, 2013): 1548–53. https://doi.org/10.1073/pnas.1213235110. Full Text

Jiang, Zhonghao, Shan Zhu, Rui Ye, Yan Xue, Amelia Chen, Lizhe An, and Zhen-Ming Pei. “Relationship between NaCl- and H2O2-induced cytosolic Ca2+ increases in response to stress in Arabidopsis..” Plos One 8, no. 10 (January 2013). https://doi.org/10.1371/journal.pone.0076130. Full Text

Liu, T. W., W. J. Hu, X. Q. Wang, L. Niu, B. Fu, F. H. Wu, Z. M. Pei, and H. L. Zheng. “RETRACTED ARTICLE: A 2-D DIGE analysis of simulated acid rain-responsive proteins in Pinus massoniana needles.” Trees  Structure and Function 26, no. 5 (October 1, 2012). https://doi.org/10.1007/s00468-012-0750-3. Full Text

Wang, Wen-Hua, Xiao-Qian Yi, Ai-Dong Han, Ting-Wu Liu, Juan Chen, Fei-Hua Wu, Xue-Jun Dong, Jun-Xian He, Zhen-Ming Pei, and Hai-Lei Zheng. “Calcium-sensing receptor regulates stomatal closure through hydrogen peroxide and nitric oxide in response to extracellular calcium in Arabidopsis..” Journal of Experimental Botany 63, no. 1 (January 2012): 177–90. https://doi.org/10.1093/jxb/err259. Full Text

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