L. Ryan Baugh

Associate Professor of Biology

Office: 
4314 French Family Science Center, Duke Box 90338, Durham, NC 27708
Campus Box: 
Duke Box 90338, Durham, NC 27708-4129
Phone: 
(919) 613-8179
We study nutritional control of development in the roundworm Caenorhabditis elegans. We are interested in the signaling pathways and gene regulatory mechanisms that enable the worm to reversibly arrest development and resist stress in response to starvation. We are also interested in epigenetic mechanisms that mediate transgenerational effects of starvation.

Education

  • Ph.D., Harvard University 2004

  • B.S., University of Georgia at Athens 1997

Baugh, L Ryan, and Craig P. Hunter. “MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans..” Genes & Development 20, no. 24 (December 2006): 3342–46. https://doi.org/10.1101/gad.1507606. Full Text

Heng, X., D. Erickson, L. R. Baugh, Z. Yaqoob, P. W. Sternberg, D. Psaltis, and C. Yang. “Optofluidic microscope: A novel high resolution microscope-on-a-chip system.” Leos Summer Topical Meeting, December 1, 2006, 15–16.

Heng, X., X. Cui, D. Erickson, L. R. Baugh, P. W. Sternberg, D. Psaltis, and C. Yang. “A compact optofluidic microscope.” Proceedings of Spie  the International Society for Optical Engineering 6329 (December 1, 2006). https://doi.org/10.1117/12.678940. Full Text

Heng, Xin, David Erickson, L Ryan Baugh, Zahid Yaqoob, Paul W. Sternberg, Demetri Psaltis, and Changhuei Yang. “Optofluidic microscopy--a method for implementing a high resolution optical microscope on a chip..” Lab on a Chip 6, no. 10 (October 2006): 1274–76. https://doi.org/10.1039/b604676b. Full Text

Baugh, L Ryan, and Paul W. Sternberg. “DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest..” Current Biology : Cb 16, no. 8 (April 2006): 780–85. https://doi.org/10.1016/j.cub.2006.03.021. Full Text

Heng, X., D. Erickson, L. R. Baugh, Z. Yaqoob, P. W. Sternberg, D. Psaltis, and C. Yang. “Optofluidic microscope - A novel microscope-on-a-chip system.” Optics Infobase Conference Papers, January 1, 2006.

Baugh, L Ryan, Andrew A. Hill, Julia M. Claggett, Kate Hill-Harfe, Joanne C. Wen, Donna K. Slonim, Eugene L. Brown, and Craig P. Hunter. “The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo..” Development (Cambridge, England) 132, no. 8 (April 2005): 1843–54. https://doi.org/10.1242/dev.01782. Full Text

Baugh, L Ryan, Joanne C. Wen, Andrew A. Hill, Donna K. Slonim, Eugene L. Brown, and Craig P. Hunter. “Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions..” Genome Biology 6, no. 5 (January 2005). https://doi.org/10.1186/gb-2005-6-5-r45. Full Text Open Access Copy

Baugh, L Ryan, Andrew A. Hill, Donna K. Slonim, Eugene L. Brown, and Craig P. Hunter. “Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome..” Development (Cambridge, England) 130, no. 5 (March 2003): 889–900. https://doi.org/10.1242/dev.00302. Full Text

Huet, François, Jeffrey T. Lu, Kyl V. Myrick, L Ryan Baugh, Madeline A. Crosby, and William M. Gelbart. “A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation..” Proceedings of the National Academy of Sciences of the United States of America 99, no. 15 (July 2, 2002): 9948–53. https://doi.org/10.1073/pnas.142310099. Full Text

Pages