Kenneth Daniel Poss
Professor of Biology
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology
Education
Postdoctoral Fellow, Cardiology, Children's Hospital 2000 - 2003
Research Fellow, University of Utah 1998 - 2000
Ph.D., Massachusetts Institute of Technology 1998
Poss, K. D., and B. Kühn. Preface. Vol. 2158, 2021.
Major, R. J., and K. D. Poss. “III. Does heart regeneration occur?: B. Zebrafish heart regeneration.” In Heart Regeneration: Stem Cells and Beyond, 59–80, 2012. https://doi.org/10.1142/9789814299817_0003. Full Text
De Simone, Alessandro, Maya N. Evanitsky, Luke Hayden, Ben D. Cox, Julia Wang, Valerie A. Tornini, Jianhong Ou, Anna Chao, Kenneth D. Poss, and Stefano Di Talia. “Control of osteoblast regeneration by a train of Erk activity waves.” Nature, January 6, 2021. https://doi.org/10.1038/s41586-020-03085-8. Full Text
Sun, Fei, Adam R. Shoffner, and Kenneth D. Poss. “A Genetic Cardiomyocyte Ablation Model for the Study of Heart Regeneration in Zebrafish.” Methods Mol Biol 2158 (2021): 71–80. https://doi.org/10.1007/978-1-0716-0668-1_7. Full Text
Chen, Anzhi, Yanchao Han, and Kenneth D. Poss. “Regulation of zebrafish fin regeneration by vitamin D signaling.” Dev Dyn, October 16, 2020. https://doi.org/10.1002/dvdy.261. Full Text
Ramkumar, Nitya, Fei Sun, and Kenneth D. Poss. “Tissue Repair: A Tendon-see to Regenerate.” Curr Biol 30, no. 17 (September 7, 2020): R1001–3. https://doi.org/10.1016/j.cub.2020.06.089. Full Text
Goldman, Joseph A., and Kenneth D. Poss. “Gene regulatory programmes of tissue regeneration.” Nat Rev Genet 21, no. 9 (September 2020): 511–25. https://doi.org/10.1038/s41576-020-0239-7. Full Text
Shoffner, Adam, Valentina Cigliola, Nutishia Lee, Jianhong Ou, and Kenneth D. Poss. “Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration.” Cell Rep 32, no. 9 (September 1, 2020): 108089. https://doi.org/10.1016/j.celrep.2020.108089. Full Text
Thompson, John D., Jianhong Ou, Nutishia Lee, Kwangdeok Shin, Valentina Cigliola, Lingyun Song, Gregory E. Crawford, Junsu Kang, and Kenneth D. Poss. “Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration.” Development 147, no. 14 (July 30, 2020). https://doi.org/10.1242/dev.191262. Full Text
Cigliola, Valentina, Clayton J. Becker, and Kenneth D. Poss. “Building bridges, not walls: spinal cord regeneration in zebrafish.” Dis Model Mech 13, no. 5 (May 27, 2020). https://doi.org/10.1242/dmm.044131. Full Text
Pronobis, Mira I., and Kenneth D. Poss. “Signals for cardiomyocyte proliferation during zebrafish heart regeneration.” Curr Opin Physiol 14 (April 2020): 78–85. https://doi.org/10.1016/j.cophys.2020.02.002. Full Text
Wang, Zhaohui, Yang Li, Bing Hou, Mira I. Pronobis, Mingqiao Wang, Yuemeng Wang, Guangcun Cheng, et al. “An array of 60,000 antibodies for proteome-scale antibody generation and target discovery.” Sci Adv 6, no. 11 (March 2020): eaax2271. https://doi.org/10.1126/sciadv.aax2271. Full Text
Pages
Merriman, A. F., C. Chen, and K. D. Poss. “Identification of new regeneration mutants in zebrafish by a forward genetic screen.” In Molecular Biology of the Cell, Vol. 26. AMER SOC CELL BIOLOGY, 2015.
Waxman, Joshua S., Brian R. Keegan, Richard W. Roberts, Kenneth D. Poss, and Deborah Yelon. “Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish.” In Developmental Biology, 319:482–482. Elsevier BV, 2008. https://doi.org/10.1016/j.ydbio.2008.05.060. Full Text
Kikuchi, Kazu, and Kenneth D. Poss. “Cardiac progenitors during zebrafish heart regeneration.” In Circulation Research, 101:E57–E57. LIPPINCOTT WILLIAMS & WILKINS, 2007.
Lee, Y., S. Grill, M. Murphy-Ryan, and K. D. Poss. “A proximodistal gradient of Fgf signaling defines position-dependent rates of zebrafish fin regeneration.” In Developmental Biology, 283:642–642. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005.
Selected Grants
Leveraging zebrafish models to dissect and enhance heart regeneration awarded by National Institutes of Health (Principal Investigator). 2020 to 2027
Genetic and Genomics Training Grant awarded by National Institutes of Health (Mentor). 2020 to 2025
Genetic approaches to skin regeneration in zebrafish awarded by National Institutes of Health (Mentor). 2020 to 2025
LIVE IMAGING OF BONE REGENERATION IN ZEBRAFISH awarded by National Institutes of Health (Co-Principal Investigator). 2020 to 2025
Advanced Immunobiology Traning Program for Surgeons awarded by National Institutes of Health (Mentor). 2019 to 2024
An integrative cellular blueprint of vertebrate tissue development awarded by University of California - San Diego (Co-Principal Investigator). 2018 to 2023
Dissecting the dynamics of vertebrate brain regeneration awarded by National Institutes of Health (Principal Investigator). 2020 to 2022
IRES Track 1 IRTG Engaged in Dissecting and Reengineering the Regulatory Genome awarded by National Science Foundation (Mentor). 2019 to 2022
Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health (Mentor). 2001 to 2022
Eliciting heart regeneration through cardiomyocyte division awarded by Fondation Leducq (Principal Investigator). 2016 to 2021