Eric P. Spana

Associate Professor of the Practice of Biology

130 Science Drive, 0050 Biological Sciences Bldg, Durham, NC 27708
Campus Box: 
Box 90338, Durham, NC 27708-1000
(919) 613-8208


  • Ph.D., University of Illinois, Urbana-Champaign 1995

  • B.S., University of Pittsburgh 1989

Spana, Eric P., Amanda B. Abrams, Katharine T. Ellis, Jason C. Klein, Brandon T. Ruderman, Alvin H. Shi, Daniel Zhu, Andrea Stewart, and Susan May. “speck, First Identified in Drosophila melanogaster in 1910, Is Encoded by the Arylalkalamine N-Acetyltransferase (AANAT1) Gene.G3 (Bethesda) 10, no. 9 (September 2, 2020): 3387–98. Full Text

Leung, Wilson, Christopher D. Shaffer, Elizabeth J. Chen, Thomas J. Quisenberry, Kevin Ko, John M. Braverman, Thomas C. Giarla, et al. “Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element.G3 (Bethesda, Md.) 7, no. 8 (August 7, 2017): 2439–60. Full Text

Seeds, Andrew M., Marco M. Tsui, Christine Sunu, Eric P. Spana, and John D. York. “Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila.Proc Natl Acad Sci U S A 112, no. 51 (December 22, 2015): 15660–65. Full Text

Leung, Wilson, Christopher D. Shaffer, Laura K. Reed, Sheryl T. Smith, William Barshop, William Dirkes, Matthew Dothager, et al. “Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.G3 (Bethesda, Md.) 5, no. 5 (March 4, 2015): 719–40. Full Text

Reitman, Zachary J., Sergey A. Sinenko, Eric P. Spana, and Hai Yan. “Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila.Blood 125, no. 2 (January 8, 2015): 336–45. Full Text

Shaffer, Christopher D., Consuelo J. Alvarez, April E. Bednarski, David Dunbar, Anya L. Goodman, Catherine Reinke, Anne G. Rosenwald, et al. “A course-based research experience: how benefits change with increased investment in instructional time.Cbe Life Sciences Education 13, no. 1 (January 2014): 111–30. Full Text

Lopatto, David, Charles Hauser, Christopher J. Jones, Don Paetkau, Vidya Chandrasekaran, David Dunbar, Christy MacKinnon, et al. “A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics.Cbe Life Sciences Education 13, no. 4 (January 2014): 711–23. Full Text

Cook, R Kimberley, Megan E. Deal, Jennifer A. Deal, Russell D. Garton, C Adam Brown, Megan E. Ward, Rachel S. Andrade, Eric P. Spana, Thomas C. Kaufman, and Kevin R. Cook. “A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications.Genetics 186, no. 4 (December 2010): 1095–1109. Full Text

Ni, Ting, David L. Corcoran, Elizabeth A. Rach, Shen Song, Eric P. Spana, Yuan Gao, Uwe Ohler, and Jun Zhu. “A paired-end sequencing strategy to map the complex landscape of transcription initiation.Nat Methods 7, no. 7 (July 2010): 521–27. Full Text

Maynard, Jason C., Trang Pham, Tianli Zheng, Angela Jockheck-Clark, Helen B. Rankin, Christopher B. Newgard, Eric P. Spana, and Christopher V. Nicchitta. “Gp93, the Drosophila GRP94 ortholog, is required for gut epithelial homeostasis and nutrient assimilation-coupled growth control.Dev Biol 339, no. 2 (March 15, 2010): 295–306. Full Text


Selected Grants

Modeling the structure & evolution of regulatory regions in eukaryotic genomes awarded by National Institutes of Health (Consultant). 2007 to 2013