This course discusses the origins of cellular life on Earth and beyond. We will ask: How did life originate? What are the limits of conditions that sustain life? Is there life elsewhere in the universe? How would we know life if we found it elsewhere (i.e., how is life defined)? This discussion-based course will delve into the literature reporting the biological and astrobiological research community’s response to life’s “big questions.” Recommended prerequisite: Biology 201L or 203L, Chemistry 201DL, and Biology 212L.