Zhen-Ming Pei

Associate Professor of Biology

3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.


  • Ph.D., Shanghai Institute of Plant Physiology 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Pei, Z-M, Ghassemian, M, Kwak, CM, McCourt, P, and Schroeder, JI. "Role of farnesyltransferase in ABA regulation of guard cell anion channels and plant water loss." Science 282, no. 5387 (1998): 287-290. Full Text

Pei, Z-M, Schroeder, JI, and Schwarz, M. "Background ion channel activities in Arabidopsis guard cells and review of ion channel regulation by protein phosphorylation events." Journal of Experimental Botany 49, no. SPEC. ISS. (1998): 319-328.

Ichida, AM, Pei, Z-M, Baizabal-Aguirre, VM, Turner, KJ, and Schroeder, JI. "Expression of a Cs+-resistant guard cell K+ channel confers Cs+-resistant, light-induced stomatal opening in transgenic Arabidopsis." Plant Cell 9, no. 10 (1997): 1843-1857. Full Text

Pei, Z-M, Kuchitsu, K, Ward, JM, Schwarz, M, and Schroeder, JI. "Differential abscisic acid regulation of guard cell slow anion channels in arabidopsis wild-type and abi1 and abi2 mutants." Plant Cell 9, no. 3 (1997): 409-423. Full Text

Pei, Z-M, Ward, JM, Harper, JF, and Schroeder, JI. "A novel chloride channel in Vicia faba guard cell vacuoles activated by the serine/threonine kinase, CDPK." EMBO Journal 15, no. 23 (1996): 6564-6574.

Pei, Z, Fu, W, Guo, L, and Tang, Z. "Effect of salt stress on photosystem II heterogeneity in wheat leaves." Science in China, Series C: Life Sciences 39, no. 5 (1996): 501-510.

Ward, JM, Pei, Z-M, and Schroeder, JI. "Roles of ion channels in initiation of signal transduction in higher plants." Plant Cell 7 (1995): 833-844. (Academic Article)