Zhen-Ming Pei

Associate Professor of Biology

3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.


  • Ph.D., Shanghai Institute of Plant Physiology 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Pei, Z-M, and Kuchitsu, K. "Early ABA signaling events in guard cells." Journal of Plant Growth Regulation 24, no. 4 (2005): 296-307. Full Text

He, Y, Tang, R-H, Hao, Y, Stevens, RD, Cook, CW, Ahn, SM, Jing, L, Yang, Z, Chen, L, Guo, F, Fiorani, F, Jackson, RB, Crawford, NM, and Pei, Z-M. "Nitric oxide represses the Arabidopsis floral transition." Science (New York, N.Y.) 305, no. 5692 (September 2004): 1968-1971. Full Text

Han, S, Tang, R, Anderson, LK, Woerner, TE, and Pei, Z-M. "A cell surface receptor mediates extracellular Ca(2+) sensing in guard cells." Nature 425, no. 6954 (September 2003): 196-200. Full Text

Kwak, JM, Mori, IC, Pei, Z-M, Leonhardt, N, Torres, MA, Dangl, JL, Bloom, RE, Bodde, S, Jones, JDG, and Schroeder, JI. "NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis." The Embo Journal 22, no. 11 (June 2003): 2623-2633. Full Text

Shang, Y, Yang, P, and Pei, Z. "Research at channel level on the effect of LaCl3 on Radish (Raphanus satirus L.) vacuolar membrane." Chinese Science Bulletin 47, no. 2 (2002): 111-115.

Yang, P, Shang, YF, and Pei, ZM. "Action Mechanism Research of Lanthanons to Slow Vacuolar Ion Channels in Raphanus Satirus L. (Xinlimei) Radish by Patch-Clamp." Chinese Chemical Letters 12, no. 9 (2001): 813-814.

Pei, Z-M, Murata, Y, Benning, G, Thomine, S, Klüsener, B, Allen, GJ, Grill, E, and Schroeder, JI. "Calcium channels activated by hydrogen peroxide mediate abscisic acidsignalling in guard cells." Nature 406, no. 6797 (August 2000): 731-734. Full Text