Zhen-Ming Pei

Associate Professor of Biology

3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.


  • Ph.D., Shanghai Institute of Plant Physiology 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Ru, QM, Xiao, Q, Lin, P, Pei, ZM, and Zheng, HL. "Short- and long-term effects of NaCl on physiological and biochemical characteristics in leaves of a true mangrove, Kandelia candel." Russian Journal of Plant Physiology 56, no. 3 (2009): 363-369. Full Text

Ru, Q-M, Pei, Z-M, and Zheng, H-L. "In vitro studies on antioxidant and antimicrobial activities of polysaccharide from Lycoris aurea." Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 31, no. 10 (2008): 1536-1540.

Pei, Z-M, and Gilroy, S. "Calcium signals and their regulation." Annual Plant Reviews: Intracellular Signaling in Plants 33 (2008): 137-162. (Academic Article)

Liu, WZ, Zhang, RJ, Pei, Z-M, and He, YK. "The signal transduction of nitric oxide in plants." Prog Nat Sci 18, no. 1 (2008): 10-24. (Academic Article)

Tang, R-H, Han, S, Zheng, H, Cook, CW, Choi, CS, Woerner, TE, Jackson, RB, and Pei, Z-M. "Coupling diurnal cytosolic Ca2+ oscillations to the CAS-IP3 pathway in Arabidopsis." Science 315, no. 5817 (March 9, 2007): 1423-1426. Full Text

Qiang, X, Qiaomei, R, Feihua, W, Xuan, H, Zhenming, P, and Hailei, Z. "Nitric Oxide Alleviates Oxidative Stress Caused by Lanthanum in Rice Leaves." Journal of Rare Earths 25, no. 5 (2007): 631-636. Full Text

Zhao, X, Pei, Z-M, and He, Y-K. "Extracellular Ca2+ signaling: first messenger in animals and plants." Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 29, no. 3 (2007): 269-275.

Pei, Z-M, and Kuchitsu, K. "Early ABA signaling events in guard cells." Journal of Plant Growth Regulation 24, no. 4 (2005): 296-307. Full Text

He, Y, Tang, R-H, Hao, Y, Stevens, RD, Cook, CW, Ahn, SM, Jing, L, Yang, Z, Chen, L, Guo, F, Fiorani, F, Jackson, RB, Crawford, NM, and Pei, Z-M. "Nitric oxide represses the Arabidopsis floral transition." Science 305, no. 5692 (September 24, 2004): 1968-1971. Full Text

Han, S, Tang, R, Anderson, LK, Woerner, TE, and Pei, Z-M. "A cell surface receptor mediates extracellular Ca(2+) sensing in guard cells." Nature 425, no. 6954 (September 11, 2003): 196-200. Full Text