Zhen-Ming Pei

Associate Professor of Biology

3102 Ffsc, Duke University, Durham, NC 27708-1000
Campus Box: 
Box 90338, Duke University, Durham, NC 27708-1000
(919) 613-8152
My laboratory is interested in the early signaling events by which plants sense environmental signals and decode to give the appropriate responses. Upon perception of external signals, cell surface receptors trigger an increase in cytosolic free calcium concentration, which is mediated by ion channels. Our long-term goals are to identify these receptors and ion channels, isolate their interacting components, and assign molecular functions to them. Currently, we are using multidisciplinary approaches of biophysics, biochemistry, cell biology, molecular genetics, and function genomics to dissect the signaling cascades of external calcium as well as nitric oxide in the model plant Arabidopsis.


  • Ph.D., Shanghai Institute of Plant Physiology 1993

  • M.S., Fudan University (China) 1990

  • B.S., Lanzhou University (China) 1985

Hu, WJ, Chen, J, Liu, TW, Wu, Q, Wang, WH, Liu, X, Shen, ZJ, Simon, M, Chen, J, Wu, FH, Pei, ZM, and Zheng, HL. "Proteome and calcium-related gene expression in Pinus massoniana needles in response to acid rain under different calcium levels." Plant and Soil 380, no. 1 (January 1, 2014): 285-303. Full Text

Liu, W-Z, Kong, D-D, Gu, X-X, Gao, H-B, Wang, J-Z, Xia, M, Gao, Q, Tian, L-L, Xu, Z-H, Bao, F, Hu, Y, Ye, N-S, Pei, Z-M, and He, Y-K. "Cytokinins can act as suppressors of nitric oxide in Arabidopsis." Proceedings of the National Academy of Sciences of the United States of America 110, no. 4 (January 14, 2013): 1548-1553. Full Text

Jiang, Z, Zhu, S, Ye, R, Xue, Y, Chen, A, An, L, and Pei, Z-M. "Relationship between NaCl- and H2O2-Induced Cytosolic Ca2+ Increases in Response to Stress in Arabidopsis." PLoS ONE 8, no. 10 (2013). Full Text

Liu, T-W, Hu, W-J, Wang, X-Q, Niu, L, Fu, B, Wu, F-H, Pei, Z-M, and Zheng, H-L. "RETRACTED ARTICLE: A 2-D DIGE analysis of simulated acid rain-responsive proteins in Pinus massoniana needles." Trees - Structure and Function 26, no. 5 (2012): 1677--. Full Text

Wang, W-H, Yi, X-Q, Han, A-D, Liu, T-W, Chen, J, Wu, F-H, Dong, X-J, He, J-X, Pei, Z-M, and Zheng, H-L. "Calcium-sensing receptor regulates stomatal closure through hydrogen peroxide and nitric oxide in response to extracellular calcium in Arabidopsis." Journal of Experimental Botany 63, no. 1 (2012): 177-190. Full Text

Huang, S-S, Chen, J, Dong, X-J, Patton, J, Pei, Z-M, and Zheng, H-L. "Calcium and calcium receptor CAS promote Arabidopsis thaliana de-etiolation." Physiologia Plantarum 144, no. 1 (2012): 73-82. Full Text

Chen, J, Wu, F-H, Liu, T-W, Chen, L, Xiao, Q, Dong, X-J, He, J-X, Pei, Z-M, and Zheng, H-L. "Emissions of nitric oxide from 79 plant species in response to simulated nitrogen deposition." Environmental Pollution 160, no. 1 (2012): 192-200. Full Text

Chen, J, Wu, F-H, Wang, W-H, Zheng, C-J, Lin, G-H, Dong, X-J, He, J-X, Pei, Z-M, and Zheng, H-L. "Hydrogen sulphide enhances photosynthesis through promoting chloroplast biogenesis, photosynthetic enzyme expression, and thiol redox modification in Spinacia oleracea seedlings." Journal of Experimental Botany 62, no. 13 (2011): 4481-4493. Full Text