Ryan Ryan Baugh

Associate Professor of Biology

4314 French Family Science Center, Duke Box 90338, Durham, NC 27708
Campus Box: 
Duke Box 90338, Durham, NC 27708-4129
(919) 613-8179
We study nutritional control of development in the roundworm Caenorhabditis elegans. We are interested in the signaling pathways and gene regulatory mechanisms that enable the worm to reversibly arrest development and resist stress in response to starvation. We are also interested in epigenetic mechanisms that mediate transgenerational effects of starvation.


  • Ph.D., Harvard University 2004

  • B.S., University of Georgia at Athens 1997

Kaplan, REW, and Baugh, LR. "L1 arrest, daf-16/FoxO and nonautonomous control of post-embryonic development." Worm 5, no. 2 (April 6, 2016): e1175196-. Full Text Open Access Copy

Kaplan, REW, Chen, Y, Moore, BT, Jordan, JM, Maxwell, CS, Schindler, AJ, and Baugh, LR. "dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest." PLoS genetics 11, no. 12 (December 11, 2015): e1005731-. Full Text Open Access Copy

Jobson, MA, Jordan, JM, Sandrof, MA, Hibshman, JD, Lennox, AL, and Baugh, LR. "Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans." Genetics 201, no. 1 (September 2015): 201-212. Full Text Open Access Copy

Chen, Y, and Baugh, LR. "Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest." Developmental Biology 394, no. 2 (October 15, 2014): 314-326. Full Text

Maxwell, CS, Kruesi, WS, Core, LJ, Kurhanewicz, N, Waters, CT, Lewarch, CL, Antoshechkin, I, Lis, JT, Meyer, BJ, and Baugh, LR. "Pol II docking and pausing at growth and stress genes in C. elegans." Cell reports 6, no. 3 (February 2014): 455-466. Full Text Open Access Copy

Artyukhin, AB, Yim, JJ, Srinivasan, J, Izrayelit, Y, Bose, N, von Reuss, SH, Jo, Y, Jordan, JM, Baugh, LR, Cheong, M, Sternberg, PW, Avery, L, and Schroeder, FC. "Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans." The Journal of Biological Chemistry 288, no. 26 (June 2013): 18778-18783. Full Text Open Access Copy

Moore, BT, Jordan, JM, and Baugh, LR. "WormSizer: high-throughput analysis of nematode size and shape." Plos One 8, no. 2 (January 2013): e57142-null. Full Text Open Access Copy

Maxwell, CS, Antoshechkin, I, Kurhanewicz, N, Belsky, JA, and Baugh, LR. "Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans." Genome Research 22, no. 10 (October 2012): 1920-1929. Full Text Open Access Copy