L. Ryan Baugh

Associate Professor of Biology

Office: 
4314 French Family Science Center, Duke Box 90338, Durham, NC 27708
Campus Box: 
Duke Box 90338, Durham, NC 27708-4129
Phone: 
(919) 613-8179
We study nutritional control of development in the roundworm Caenorhabditis elegans. We are interested in the signaling pathways and gene regulatory mechanisms that enable the worm to reversibly arrest development and resist stress in response to starvation. We are also interested in epigenetic mechanisms that mediate transgenerational effects of starvation.

Education

  • Ph.D., Harvard University 2004

  • B.S., University of Georgia at Athens 1997

Zaslaver, A, Baugh, LR, and Sternberg, PW. "Metazoan operons accelerate recovery from growth-arrested states." Cell 145, no. 6 (2011): 981-992. Full Text Open Access Copy

Baugh, LR. "Staging worms for next-generation analysis." Nature Methods 6, no. 10 (October 2009): 727-728. Full Text

Baugh, LR, DeModena, J, and Sternberg, PW. "RNA Pol II accumulates at promoters of growth genes during developmental arrest." Science 324, no. 5923 (2009): 92-94. Full Text

Yanai, I, Baugh, LR, Smith, JJ, Roehrig, C, Shen-Orr, SS, Claggett, JM, Hill, AA, Slonim, DK, and Hunter, CP. "Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression." Molecular Systems Biology 4 (2008). Full Text Open Access Copy

Baugh, LR, and Sternberg, PW. "DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest." Current Biology : Cb 16, no. 8 (April 2006): 780-785. Full Text

Heng, X, Erickson, D, Baugh, LR, Yaqoob, Z, Sternberg, PW, Psaltis, D, and Yang, C. "Optofluidic microscope - A novel microscope-on-a-chip system." Optics InfoBase Conference Papers (January 1, 2006).

Baugh, LR, and Hunter, CP. "MyoD, modularity, and myogenesis: Conservation of regulators and redundancy in C. elegans." Genes and Development 20, no. 24 (2006): 3342-3346. Full Text

Heng, X, Erickson, D, Baugh, LR, Yaqoob, Z, Sternberg, PW, Psaltis, D, and Yang, C. "Optofluidic microscopy - A method for implementing a high resolution optical microscope on a chip." Lab on a Chip - Miniaturisation for Chemistry and Biology 6, no. 10 (2006): 1274-1276. Full Text

Heng, X, Erickson, D, Baugh, LR, Yaqoob, Z, Sternberg, PW, Psaltis, D, and Yang, C. "Optofluidic microscope: A novel high resolution microscope-on-a-chip system." LEOS Summer Topical Meeting (2006): 15-16.

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