L. Ryan Baugh

Associate Professor of Biology

Office: 
4314 French Family Science Center, Duke Box 90338, Durham, NC 27708
Campus Box: 
Duke Box 90338, Durham, NC 27708-4129
Phone: 
(919) 613-8179
We study nutritional control of development in the roundworm Caenorhabditis elegans. We are interested in the signaling pathways and gene regulatory mechanisms that enable the worm to reversibly arrest development and resist stress in response to starvation. We are also interested in epigenetic mechanisms that mediate transgenerational effects of starvation.

Education

  • Ph.D., Harvard University 2004

  • B.S., University of Georgia at Athens 1997

Baugh, LR, and Hunter, CP. "MyoD, modularity, and myogenesis: Conservation of regulators and redundancy in C. elegans." Genes and Development 20, no. 24 (2006): 3342-3346. Full Text

Heng, X, Erickson, D, Baugh, LR, Yaqoob, Z, Sternberg, PW, Psaltis, D, and Yang, C. "Optofluidic microscopy - A method for implementing a high resolution optical microscope on a chip." Lab on a Chip - Miniaturisation for Chemistry and Biology 6, no. 10 (2006): 1274-1276. Full Text

Heng, X, Erickson, D, Baugh, LR, Yaqoob, Z, Sternberg, PW, Psaltis, D, and Yang, C. "Optofluidic microscope: A novel high resolution microscope-on-a-chip system." LEOS Summer Topical Meeting (2006): 15-16.

Heng, X, Cui, X, Erickson, D, Baugh, LR, Sternberg, PW, Psaltis, D, and Yang, C. "A compact optofluidic microscope." Proceedings of SPIE - The International Society for Optical Engineering 6329 (2006). Full Text

Baugh, LR, Hill, AA, Claggett, JM, Hill-Harfe, K, Wen, JC, Slonim, DK, Brown, EL, and Hunter, CP. "The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo." Development 132, no. 8 (April 2005): 1843-1854. Full Text

Baugh, LR, Wen, JC, Hill, AA, Slonim, DK, Brown, EL, and Hunter, CP. "Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions." Genome Biol 6, no. 5 (2005): R45-. Full Text Open Access Copy

Baugh, LR, Hill, AA, Slonim, DK, Brown, EL, and Hunter, CP. "Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome." Development 130, no. 5 (2003): 889-900. Full Text

Huet, F, Lu, JT, Myrick, KV, Baugh, LR, Crosby, MA, and Gelbart, WM. "A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation." Proceedings of the National Academy of Sciences of the United States of America 99, no. 15 (2002): 9948-9953. Full Text

Harvey, AJ, Speksnijder, G, Baugh, LR, Morris, JA, and Ivarie, R. "Expression of exogenous protein in the egg white of transgenic chickens." Nature Biotechnology 20, no. 4 (2002): 396-399. Full Text

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