L. Ryan Baugh

Associate Professor of Biology

4314 French Family Science Center, Duke Box 90338, Durham, NC 27708
Campus Box: 
Duke Box 90338, Durham, NC 27708-4129
(919) 613-8179
We study nutritional control of development in the roundworm Caenorhabditis elegans. We are interested in the signaling pathways and gene regulatory mechanisms that enable the worm to reversibly arrest development and resist stress in response to starvation. We are also interested in epigenetic mechanisms that mediate transgenerational effects of starvation.


  • Ph.D., Harvard University 2004

  • B.S., University of Georgia at Athens 1997

Moore, BT, Jordan, JM, and Baugh, LR. "WormSizer: high-throughput analysis of nematode size and shape." PLoS One 8, no. 2 (2013): e57142-. Full Text Open Access Copy

Artyukhin, AB, Yim, JJ, Srinivasan, J, Izrayelit, Y, Bose, N, Reuss, SHV, Jo, Y, Jordan, JM, Baugh, LR, Cheong, M, Sternberg, PW, Avery, L, and Schroeder, FC. "Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in caenorhabditis elegans." Journal of Biological Chemistry 288, no. 26 (2013): 18778-18783. Full Text Open Access Copy

Maxwell, CS, Antoshechkin, I, Kurhanewicz, N, Belsky, JA, and Baugh, LR. "Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans." Genome Res 22, no. 10 (October 2012): 1920-1929. Full Text Open Access Copy

Zaslaver, A, Baugh, LR, and Sternberg, PW. "Metazoan operons accelerate recovery from growth-arrested states." Cell 145, no. 6 (2011): 981-992. Full Text Open Access Copy

Baugh, LR, DeModena, J, and Sternberg, PW. "RNA Pol II accumulates at promoters of growth genes during developmental arrest." Science 324, no. 5923 (2009): 92-94. Full Text

Baugh, LR. "Staging worms for next-generation analysis." Nature Methods 6, no. 10 (2009): 727-728. Full Text

Yanai, I, Baugh, LR, Smith, JJ, Roehrig, C, Shen-Orr, SS, Claggett, JM, Hill, AA, Slonim, DK, and Hunter, CP. "Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression." Molecular Systems Biology 4 (2008). Full Text Open Access Copy

Heng, X, Erickson, D, Baugh, LR, Yaqoob, Z, Sternberg, PW, Psaltis, D, and Yang, C. "Optofluidic microscope - A novel microscope-on-a-chip system." Optics InfoBase Conference Papers (January 1, 2006).