Eric P. Spana

Assistant Professor of the Practice in the Department of Biology

130 Science Drive, 0050 Biological Sciences Bldg, Durham, NC 27708
Campus Box: 
Box 90338, Durham, NC 27708-1000
(919) 613-8208


  • Ph.D., University of Illinois -- Urbana-Champaign 1995

  • B.S., University of Pittsburgh 1989

Leung, W, Shaffer, CD, Chen, EJ, Quisenberry, TJ, Ko, K, Braverman, JM, Giarla, TC, Mortimer, NT, Reed, LK, Smith, ST, Robic, S, McCartha, SR, Perry, DR, Prescod, LM, Sheppard, ZA, Saville, KJ, McClish, A, Morlock, EA, Sochor, VR, Stanton, B, Veysey-White, IC, Revie, D, Jimenez, LA, Palomino, JJ, Patao, MD, Patao, SM, Himelblau, ET, Campbell, JD, Hertz, AL, McEvilly, MF, Wagner, AR, Youngblom, J, Bedi, B, Bettincourt, J, Duso, E, Her, M, Hilton, W, House, S, Karimi, M, Kumimoto, K, and Lee, R et al. "Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element." G3 (Bethesda, Md.) 7, no. 8 (August 2017): 2439-2460. Full Text

Seeds, AM, Tsui, MM, Sunu, C, Spana, EP, and York, JD. "Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila." Proceedings of the National Academy of Sciences of the United States of America 112, no. 51 (December 8, 2015): 15660-15665. Full Text

Leung, W, Shaffer, CD, Reed, LK, Smith, ST, Barshop, W, Dirkes, W, Dothager, M, Lee, P, Wong, J, Xiong, D, Yuan, H, Bedard, JEJ, Machone, JF, Patterson, SD, Price, AL, Turner, BA, Robic, S, Luippold, EK, McCartha, SR, Walji, TA, Walker, CA, Saville, K, Abrams, MK, Armstrong, AR, Armstrong, W, Bailey, RJ, Barberi, CR, Beck, LR, Blaker, AL, Blunden, CE, Brand, JP, Brock, EJ, Brooks, DW, Brown, M, Butzler, SC, Clark, EM, Clark, NB, Collins, AA, Cotteleer, RJ, Cullimore, PR, Dawson, SG, and Docking, CT et al. "Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution." G3 (Bethesda, Md.) 5, no. 5 (March 4, 2015): 719-740. Full Text

Reitman, ZJ, Sinenko, SA, Spana, EP, and Yan, H. "Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila." Blood 125, no. 2 (January 2015): 336-345. Full Text

Shaffer, CD, Alvarez, CJ, Bednarski, AE, Dunbar, D, Goodman, AL, Reinke, C, Rosenwald, AG, Wolyniak, MJ, Bailey, C, Barnard, D, Bazinet, C, Beach, DL, Bedard, JEJ, Bhalla, S, Braverman, J, Burg, M, Chandrasekaran, V, Chung, H-M, Clase, K, Dejong, RJ, Diangelo, JR, Du, C, Eckdahl, TT, Eisler, H, Emerson, JA, Frary, A, Frohlich, D, Gosser, Y, Govind, S, Haberman, A, Hark, AT, Hauser, C, Hoogewerf, A, Hoopes, LLM, Howell, CE, Johnson, D, Jones, CJ, Kadlec, L, Kaehler, M, and Silver Key, SC et al. "A course-based research experience: how benefits change with increased investment in instructional time." CBE life sciences education 13, no. 1 (January 2014): 111-130. Full Text

Lopatto, D, Hauser, C, Jones, CJ, Paetkau, D, Chandrasekaran, V, Dunbar, D, MacKinnon, C, Stamm, J, Alvarez, C, Barnard, D, Bedard, JEJ, Bednarski, AE, Bhalla, S, Braverman, JM, Burg, M, Chung, H-M, DeJong, RJ, DiAngelo, JR, Du, C, Eckdahl, TT, Emerson, J, Frary, A, Frohlich, D, Goodman, AL, Gosser, Y, Govind, S, Haberman, A, Hark, AT, Hoogewerf, A, Johnson, D, Kadlec, L, Kaehler, M, Key, SCS, Kokan, NP, Kopp, OR, Kuleck, GA, Lopilato, J, Martinez-Cruzado, JC, McNeil, G, Mel, S, and Nagengast, A et al. "A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics." CBE life sciences education 13, no. 4 (January 2014): 711-723. Full Text

Cook, RK, Deal, ME, Deal, JA, Garton, RD, Brown, CA, Ward, ME, Andrade, RS, Spana, EP, Kaufman, TC, and Cook, KR. "A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications." Genetics 186, no. 4 (December 2010): 1095-1109. Full Text

Ni, T, Corcoran, DL, Rach, EA, Song, S, Spana, EP, Gao, Y, Ohler, U, and Zhu, J. "A paired-end sequencing strategy to map the complex landscape of transcription initiation." Nat Methods 7, no. 7 (July 2010): 521-527. Full Text

Maynard, JC, Pham, T, Zheng, T, Jockheck-Clark, A, Rankin, HB, Newgard, CB, Spana, EP, and Nicchitta, CV. "Gp93, the Drosophila GRP94 ortholog, is required for gut epithelial homeostasis and nutrient assimilation-coupled growth control." Dev Biol 339, no. 2 (March 15, 2010): 295-306. Full Text

Zhang, Y, Malone, JH, Powell, SK, Periwal, V, Spana, E, Macalpine, DM, and Oliver, B. "Expression in aneuploid Drosophila S2 cells. (Published online)" PLoS Biol 8, no. 2 (February 23, 2010): e1000320-. Full Text Open Access Copy


Selected Grants

Modeling the structure & evolution of regulatory regions in eukaryotic genomes awarded by National Institutes of Health (Consultant). 2007 to 2013